A brief introduction to DPM
DPM (Double Prediction Method) is a secondary structure prediction which predicts the protein structural class and then the
secondary structure for the sequence (this is why Double). The DPM method consists in 4 successive steps:
Prediction of the structural class of a protein from AA composition (Nakashima et al. 1986 J. Biochem. Tokyo, 99, 153-162).
Preliminary secondary structure estimation from a simple algorithm.
Comparison between the 2 independent predictions.
Optimization of parameters and reprediction of secondary structure.