If you use this service, could you please send us a mail to npsang@ibcp.fr with details about your usage of the NPSA service (tools used, frequency, type of sequence, ..) ? Could you explain what makes this service unique for you ? Could you please add information about your country and your laboratory ? Thanks

Paste a multiple protein alignment in clustalw format below : help

Alignment boundaries :
If new alignment boundaries, keep sequences with at least residues in alignment region.

Profile HMM construction options :
Alignment mode : Global (-g) Domain Local (-s) Multi-hit local (-f)
Weighting mode : BLOSUM filtering algo (--wblosum) Gerstein/Sonnhammer/Chothia algo (--wgsc) Krogh/Mitchison max entropy algo (--wme) Henikoff position based algo (--wpb) Sibbald/Argos Voronoi algo (--wvoronoi) No sequence weighting (--wnone)
If blosum weighting mode, you can choose percent identity (--idlevel, fraction from 0 to 1):